Alifia Putri Febriyanti
Department of Pharmacy, Medical Faculty and Health Science UIN Maulana Malik Ibrahim, Malang, East Java, Indonesia

Prida Ayudianti
Department of Dermatovenerology, Medical Faculty and Health Science UIN Maulana Malik Ibrahim, Malang, East Java, Indonesia

Putri Wulan Akbar
Department of Biochemistry and Clinical Pathology, Medical Faculty and Health Science UIN Maulana Malik Ibrahim, Malang, East Java , Indonesia

Nurfianti Indriana
Department of Obstetrics and Gynecology, Medical Faculty and Health Science UIN Maulana Malik Ibrahim, Malang, East Java, Indonesia

DOI: https://doi.org/10.19184/ams.v9i3.42833

Abstract

Preeclampsia is defined as hypertension in pregnancy, which can cause maternal and fetal complications. One of the complications of perinatal outcomes is low birth weight (LBW). The degree of proteinuria describes the severity of organ disorders in preeclampsia. Therefore, proteinuria can be used as a predictor of LBW. This study aims to determine the relationship between the degree of proteinuria in preeclamptic mothers and the incidence of LBW. This research is an analytical observational study with a cross-sectional design. Sampling was carried out using a purposive sampling technique. A total of 36 preeclamptic mothers who gave birth at RSU Karsa Husada Batu in 2021 were included in this research. The chi-square test results showed a relationship between the degree of proteinuria in preeclamptic mothers and the incidence of LBW (p=0.005; CI=95%). This indicates that the higher the degree of proteinuria in preeclamptic mothers, the higher the incidence of LBW. We conclude there is a relationship between the degree of proteinuria in preeclamptic mothers and the incidence of LBW at RSU Karsa Husada Batu from January to December 2021.

Keyword: Preeclampsia, Degree of Proteinuria, LBW.

REFERENCE

1. Amaral, L. M., Wallace, K., Owens, M., & Lamarca, B. (2018). Pathophysiology and current clinical management of preeclampsia. Current Hypertension Repository, 19(8). https://doi.org/10.1007/s11906-017-0757-7

2. Bartal, M. F., Lindheimer, M. D., & Sibai, B. M. (2022). Expert Review Proteinuria during pregnancy : definition , pathophysiology , methodology , and clinical significance. The American Journal of Obstetrics & Gynecology, 226(2), S819–S834. https://doi.org/10.1016/j.ajog.2020.08.108

3. Bartal, M. F., & Sibai, B. M. (2021). Proteinuria in pregnancy : much ado about nothing , a response. The American Journal of Obstetrics & Gynecology, 224(4), 422. https://doi.org/10.1016/j.ajog.2020.11.015

4. Baumwell, S., & Karumanchi, S. A. (2007). Pre-Eclampsia : Clinical Manifestations. 02215. https://doi.org/10.1159/000101801

5. Damayanti, A., Setiyawati, N., & Margono, M. (2021). The factors causes of low birth weight in RSUD Wates Kulon Progo distrcict. Journal of Health Technology, 16(2).

6. Dong, X., Gou, W., Li, C., Wu, M., Han, Z., Li, X., & Chen, Q. (2017). Proteinuria in preeclampsia: not essential to diagnosis but related to disease severity and fetal outcomes. Pregnancy Hypertension: An International Journal of Women’s Cardiovascular Health. https://doi.org/10.1016/j.preghy.2017.03.005